nRichDX Revolution Sample Prep System
Unprecedented sample prep volumes, unparalleled simplicity
The nRichDX Revolution Sample Prep System is designed to purify cfDNA, exosomes, microvesicles, CTCs, and other cancer biomarkers from 1–20 mL of blood, plasma, urine, and other biological fluids. The patented technology is centered on the single-use Revolution nRicher Cartridge that combines extraction, enrichment, and concentration without the need for transfer steps.
The IVD-labeled nRichDX Revolution Sample Prep System is an unprecedented, innovative solution: combining an industry-leading target recovery rate of up to 80% with the ability to process total volumes up to 50 mL. The combination of larger samples and higher recovery rates translates to significantly more analytes to deliver accurate molecular diagnostic results at low allele frequencies.
The Revolution System Includes:
- Revolution Processor - PN 10081
- Revolution Cartridge Rack - PN 100305
- Drip Tray - PN 100140
- Revolution Mag Capsules (Box of 12) - PN 10080
- Revolution Mag Rack - PN 10082
Revolution Semi-Automated Workflow
nRichDX and Eppendorf have collaborated to make available a version of the best-in-class epMotion 5073m liquid handling system programmed to automate the Revolution System's wash and elution steps (the "Eppendorf Option"). For higher throughput, the Eppendorf Option can be used in conjunction with two Revolution Processors to process up to 24 samples per batch.
The Eppendorf Option requires the purchase of the Revolution Microvial Tube Rack - PN 100395.
The Eppendorf Option is intended for researchers performing Clinical Research and Research Use Only applications.* To purchase the Eppendorf Option, you may leave the nRichDX website and connect directly to Eppendorf using the button below.
*The Revolution semi-automated workflow is not labeled for IVD use, despite the fact that the Revolution cfDNA isolation kits are labeled for IVD use.
Eppendorf®, the Eppendorf logo, epT.I.P.S.®, epMotion® and Eppendorf Tubes® are registered trademarks of Eppendorf AG, Germany. epBlue™ and Eppendorf EasyCon™ are trademarks of Eppendorf AG, Germany. U.S. Design Patents are listed on http://www.eppendorf.com/ip. All rights reserved, including graphics and images. Copyright © 2015 by Eppendorf AG.
Revolution Microvial Tube Rack
The Revolution Microvial Tube Rack holds 1-24 nRicher Cartridge Microvial Tubes and is an essential part of the Revolution Semi-Automated Workflow.
Revolution Mag Capsules
Each Revolution Mag Capsule is designed to work exclusively with the nRichDX Revolution nRicher Cartridge for the isolation and purification of liquid specimens. 12 Mag Capsules each.
Revolution Mag Rack
An essential part of the elution process, the Revolution Mag Rack holds 1-12 of the 2 mL Revolution microvial tubes that are an integrated component of the Revolution nRicher Cartridge.
Revolution nRicher Cartridge
The Revolution nRicher Cartridge embodies a patented sample processing method that combines extraction, enrichment, and concentration of liquid-based assay samples, including liquid biopsy samples, without the need for transfer steps. The elimination of transfer steps facilitates a simple workflow and enables an industry-leading target recovery rate of up to 80%.
The Revolution nRicher Cartridge may not be purchased separately but is a component of the Revolution cfDNA Max 20 Kit and Revolution cfDNA Max 20XL Kit.
Revolution nRicher Cartridges pictured inside Revolution Cartridge Rack.
Revolution Cartridge Rack
The Revolution Cartridge Rack holds 1 – 12, Revolution nRicher Cartridges and is an essential part of the Revolution Sample Prep System.
Revolution cfDNA Isolation Kits
Revolution cfDNA Max 20 Kit
The Revolution cfDNA Max 20 Kit includes (24) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 3-5 mL extractions or
- (12) 6-10 mL preps or
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Revolution cfDNA Max 20XL Kit
The Revolution cfDNA Max 20XL Kit includes (8) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Revolution cfDNA Reagent Kit 0.5
The Revolution cfDNA Reagent Kit provides “reagents only” to enable the use of any excess Revolution nRicher Cartridges. No Revolution nRicher Cartridges are included. This kit has sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (12) 3-5 mL preps or
- (6) 6-10 mL preps or
- (4) 11-15 mL preps or
- (3) 16-20 mL preps