Reference Materials
Current Perspectives on Liquid Biopsy Technologies (video)
Venue: Webinar
Date: April 2023
This webinar features keynote presenter Klaus Pantel, MD, PhD. Chairman of the Institute of Tumour Biology, University Medical Center Hamburg-Eppendorf, and Founder and Chairman of the European Liquid Biopsy Society (ELBS).
The nRichDX Revolution Sample Prep System™ enables recovery of more amplifiable copies and more cancer fraction detection from cfDNA as evaluated on the MassARRAY® System
Venue: American Association for Cancer Research (AACR) Annual Meeting 2023
Date: April 2023
This poster demonstrates the Revolution System's ability to extract more amplifiable copies of cfDNA and ctDNA biomarkers from plasma samples of 5 mL and 20 mL as compared to a leading competitor's kit. Samples were spiked with cfDNA reference standard containing KRAS p.G12V mutation to a final concentration of 20ng/mL and run on the Agena Bioscience MassARRAY System.
Detection of Somatic Variants in Breast Cancer from Large Volumes of Plasma Using the nRichDX Revolution System
Venue: Molecular & Precision Medicine (TRI-CON) 2023 Annual Meeting
Date: March 2023
This poster demonstrates the Revolution cfDNA isolation kit's ability to extract circulating cell-free deoxyribonucleic acid (cfDNA) from plasma samples of up to 20 mL in a single extraction. cfDNA total yield was measured via Qubit and characterized by TapeStation, and Ct values for a well-characterized breast cancer mutation were determined.
Higher Total RNA Yields and Sequenceable RNA is Attainable Using the nRichDX Revolution Sample Prep System Total Nucleic Acid Isolation Kit
Venue: Association for Molecular Pathology (AMP) 2022 Annual Meeting & Expo
Date: November 2022
This poster demonstrates the Revolution cell-free Total Nucleic Acid Isolation Kit's ability to extract circulating cell-free total nucleic acid (cfNA) including circulating free RNA (cfRNA) from plasma samples of up to 20 mL in a single extraction. High-performance Next Generation Sequencing (NGS) results from cfRNA were obtained as compared to two competing methods.
Colli-Pee® UAS™ Combined withnRichDX Revolution System™, a Promising Urinary Cell-free DNA Collection, Preservation and Extraction Workflow
Venue: Association for Molecular Pathology (AMP) 2022 Annual Meeting & Expo
Date: November 2022
This poster demonstrates the compatibility of the Colli-Pee and UAS urine collection system from Novosanis with the nRichDX Revolution Sample Prep System for extraction of cfDNA from up to 20 mL of urine in a single extraction. cfDNA yield, purity, and other factors were compared with other sample prep methods.Molecular Profiling of Urine for Prostate Cancer Diagnosis: Opportunities and Challenges (video)
Venue: Webinar
Date: September 2022
This joint webinar with nRichDX partner Novosanis covers current opportunities and challenges of urine as a sample type for molecular profiling of prostate cancer from Keynote Presenter, Dr. Simpa Salami, Assistant Professor of Urology and Co-Director of the University of Michigan's Liquid Biopsy Core Laboratory.The Revolution Sample Prep System for Liquid Biopsy Applications (video)
Venue: Cancer Genomics Consortium (CGC) 2022 13th Annual Meeting
Date: August 2022
This video provides a brief introduction to the Revolution Sample Prep System from Nafiseh Jafari, PhD of nRichDX.
Higher cfRNA Recovery and Precision from Large Urine Sample Volumes Using the nRichDX Revolution Sample Prep System
Venue: Cancer Genomics Consortium (CGC) 2022 13th Annual Meeting
Date: August 2022
This poster demonstrates the Revolution Sample Prep System's ability to extract circulating free total nucleic acid (cfNA) and circulating free RNA (cfRNA) from urine samples of up to 20 mL in a single extraction.
Higher cfDNA Recovery and Precision from Large Urine Sample Volumes Using the nRichDX Revolution Sample Prep System
Venue: Cancer Genomics Consortium (CGC) 2022 13th Annual Meeting
Date: August 2022
This poster demonstrates the Revolution Sample Prep System's compatibility with the Novosanis® Colli-Pee® sample collection and stabilization system for recovery of cfDNA from urine samples of up to 20 mL in a single extraction.
MinION Nanopore Sequencing of cell-free DNA (cfDNA) and cell-free RNA (cfRNA) extracted from human plasma using nRichDX Revolution System
Venue: Association for Molecular Pathology (AMP) 2021 Annual Meeting
Date: November 2021
This poster demonstrates the Revolution Sample Prep System's compatibility with Oxford Nanopore Technologies MinION sequencing device for NGS sequencing of cfDNA and cfRNA.
Semi-Automated High Yield cfDNA Extraction Using nRichDX Revolution Sample Prep System on Eppendorf epMotion for Liquid Biopsy Development
Venue: Association for Molecular Pathology (AMP) 2021 Annual Meeting
Date: November 2021
This poster describes the Semi-Automated Workflow of Revolution Sample Prep on the Eppendorf epMotion 5073 liquid handler.
nRichDX Revolution Instrument and cfDNA isolation Kit for Extraction of cfDNA from Large Plasma and Urine Sample Volumes Improves Yield of Rare Targets
Venue: Association for Molecular Pathology (AMP) 2019 Annual Meeting
Date: November 2019
This poster introduces the Revolution Sample Prep System for extraction of cfDNA from plasma and urine samples as compared to a competing sample prep kit.
Assessment of the nRichDX Revolution Instrument and Isolation kit for cell-free DNA extraction from liquid biopsy
Venue: Association for Molecular Pathology (AMP) 2019 Annual Meeting
Date: November 2019
This poster from the laboratory of Dr. Gregory Tsongalis evaluand ates the nRichDX Revolution Sample Prep System for extraction of cfDNA aand