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Help define the future of liquid biopsy and extraction of rare analytes at nRichDX!

nRichDX welcomes an application, resume, or CV received directly from qualified individuals interested in working for nRichDX. See listings under Career Opportunities below.

 

Unsolicited resumes and CVs from recruiters and uncontracted third parties

nRichDX does not accept unsolicited applications, resumes, or CVs from uncontracted individual recruiters or third-party recruiting agencies ("Agency"). nRichDX will not accept unsolicited resumes from any source other than directly from the candidate. nRichDX will not pay a fee for any hire or placement resulting from indirectly receiving an unsolicited resume. nRichDX will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees.

Notice: fraudulent job offers and email scams

Please note that emails that claim to offer a job at nRichDX without an interview are fraudulent. nRichDX does not offer jobs to candidates that have not directly interviewed bonafide and current employees of nRichDX and completed nRichDX's interview process. nRichDX will never ask job applicants for money, your banking information, or to make a banking transaction - such as requesting you to deposit or cash a check, make a payment of any kind (for example, for software), or for your social security number (SSN) as part of the interview process. This article about Job Scams from the U.S. Federal Trade Commission (FTC) may help identify fraudulent job offers and scams.

Note: emails appearing to originate from "careers@nrichdxjobs.com" are fraudulent, not from nRichDX, and have been reported to the authorities.

Career Opportunities

 

Scientist


Department

Research & Development (R&D)

Location

This role is based at nRichDX in Irvine, California

Summary

nRichDX is seeking an R&D team member whose primary responsibility will be quality control and functional testing of nucleic-acid extraction kits (cfDNA/cfRNA/cfTNA/CTC-related), supporting product releases and manufacturing scale. This role will also contribute to routine R&D workflows, including method verification, troubleshooting, documentation, and data generation for continuous improvement and external deliverables.

Key Responsibilities

Kit QC & Functional Testing (Primary)

  • Own and execute functional testing plans for commercial kit lots (incoming components, in-process, and final kit performance testing).
  • Run routine QC assays, including (as applicable):
  • qPCR/RT-qPCR (recovery, inhibition checks, linearity)
  • TapeStation/Bioanalyzer (size profiles, integrity, yield QC)
  • Fluorometric quantification (Qubit/PicoGreen/RiboGreen)
  • Extraction performance checks (yield, reproducibility, carryover, contamination controls)
  • Prepare and process biological samples (plasma/urine/whole blood and contrived controls) according to SOPs.
  • Track lot performance, generate QC summaries/CoA-support data, and flag out-of-spec trends.
  • Investigate deviations and failures, perform root-cause analysis, and recommend corrective actions with R&D, Manufacturing, and Quality.

Cross-Functional Support

  • Partner with Manufacturing to ensure smooth tech transfer and readiness for scale (materials, build records, test readiness).
  • Coordinate with Quality on documentation, change control support, and release criteria.
  • Support troubleshooting of customer-reported issues by recreating conditions and documenting findings.

Routine R&D Work (Secondary)

  • Assist with protocol optimization, method verification, and robustness studies.
  • Support automation workflows as needed (e.g., Hamilton or internal platforms), including run setup, execution, and data review.
  • Maintain lab organization, instrument upkeep, reagent preparation, and inventory management.
  • Maintain high-quality documentation: lab notebooks, raw data files, SOP updates, and summary reports.

Qualifications

Required

  • B.S. in Molecular Biology, Biochemistry, Chemistry, Biomedical Engineering, or related field (M.S. preferred).
  • 2+ years hands-on experience in a molecular biology lab (industry preferred).
  • Demonstrated experience with DNA/RNA extraction and qPCR/RT-qPCR.
  • Strong attention to detail and comfort working in a structured, repeatable testing environment.
  • Ability to produce clear documentation and communicate results to cross-functional teams.

Preferred

  • Experience with cfDNA/cfRNA/cfTNA workflows, low-input samples, or liquid biopsy.
  • Experience with TapeStation/Bioanalyzer, NGS library QC, or inhibition/contamination control strategies.
  • Familiarity with GxP/ISO concepts, change control, deviations, and data integrity principles.
  • Experience supporting automation platforms (Hamilton, etc.).
  • Comfortable analyzing data in Excel; bonus for basic stats/graphing or scripting.

Skills & Attributes

  • Highly organized, reliable, and execution-focused.
  • Strong troubleshooting mindset and ability to identify patterns/trends across lots.
  • Collaborative and comfortable working with R&D, Manufacturing, and Quality.
  • Able to manage multiple tests/priorities while maintaining accuracy.

Working Conditions

  • Lab-based role handling human-derived specimens (with appropriate training and PPE).
  • May require occasional schedule flexibility to support builds, releases, or time-sensitive studies.

Success Metrics (First 3–6 Months)

  • Independently executes the functional testing plan for kit lots with minimal supervision.
  • Produces consistent, audit-ready QC documentation and summaries.
  • Helps reduce retests/failures via early detection of issues and clear root-cause investigations.
  • Contributes meaningfully to routine R&D studies and continuous improvement efforts.

 

To Apply

please see the job posting on LinkedIn and complete the application. Alternatively you may send your CV and Cover Letter to info@nrichdx.com.