Revolution Plus System
PN 2000-PLUS
The Revolution Plus Sample Prep System enables high-yield purification of cfDNA, cfRNA, and CTCs from a wide range of sample types, including plasma, urine, blood, and other bodily fluids. The system supports input volumes of up to 50 mL for cell-free analytes (cfDNA and cfRNA) and up to 100 mL for CTCs and other applications (e.g., infectious diseases).
The patented technology is centered on the single-use Revolution nRicher Cartridges that combine extraction, enrichment, and concentration without the need for yield-lowering sample transfer steps, re-elutions, or pooling multiple extractions from the same sample. Revolution Sample Prep handles small and large volume extractions with ease.
Revolution Plus is able to operate in two different modes using separate USB Keys. "Kit Mode" for extraction according to the latest approved Revolution Protocol and a user-programmable "Research Mode" (available separately).
The IVD-labeled* nRichDX Revolution Plus Sample Prep System delivers better performance, workflow, and flexibility with solutions engineered to easily deliver the highest yields of pure rare analytes from an unequaled range of liquid biopsy sample types and volumes.
*IMPORTANT NOTE: The Revolution cfDNA and cfTNA Kits when used in "Kit Mode" on the Revolution Plus Instrument are IVD-labeled. The Revolution CTC Enrichment Kit is labeled, "For Research Use Only. Not for use in diagnostic applications." even when the IVD-labeled Revolution Plus Instrument is used in Kit Mode.
Resources
Revolution cfDNA Max 20 Kit
PN 408000
Summary Product Benefits:
For input sample volumes (like plasma and urine) from 1 mL - 20 mL. Includes nRicher Cartridges and kit reagents.
- Better Performance - higher yields of cfDNA means greater assay sensitivity and fewer 'QNS' assay failures
- Greater Flexibility - widest range of input sample volume (1 mL - 20 mL) of any automated extraction kit with the unique nRicher Cartridge
- Easier Workflow - as compared to other methods which require tedious vacuum manifolds, tube extenders, manual pre-concentration steps, re-elutions, and extraction sample pooling for larger per-sample volumes
The IVD-labeled Revolution cfDNA Max 20 Kit includes (24) 50 mL nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 1-5 mL preps, or
- (12) 6-10 mL preps, or
- (8) 11-15 mL preps, or
- (6) 16-20 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Resources
Revolution cfDNA Max 20 Reagent Kit
PN 401000
Summary Product Benefits:
Kit reagents only for input sample volumes (like plasma and urine) from 1 mL - 20 mL.
- Flexibility - The same cfDNA Max 20 Revolution reagents without the nRicher Cartridges
- Efficiency - Get full utilization of all your kit's nRicher Cartridges
The IVD-labeled Revolution cfDNA Max 20 Reagent Kit provides supplemental reagents to enable the use of any excess Revolution nRicher Cartridges in the cfDNA Max 20 Kit shown above. Revolution nRicher Cartridges are not included in the reagent kit. This kit has sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 1-5 mL preps, or
- (12) 6-10 mL preps, or
- (8) 11-15 mL preps, or
- (6) 16-20 mL preps
Revolution cfDNA Max 50 Kit
PN 405000
Summary Product Benefits:
Similar to the Revolution cfDNA Max 20 Kit, but designed for larger sample volumes of 21 mL - 50 mL. Includes nRicher Cartridges and kit reagents.
- Extract from larger volumes - designed for sample volumes >20 mL in a single extraction
- Same performance, flexibility, and workflow advantages
- Runs on the Revolution Plus Processor
The IVD-labeled Revolution cfDNA Max 50 Kit includes (24) 100 mL nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 21-30 mL preps, or
- (18) 31-40 mL preps, or
- (12) 41-50 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Resources
Revolution cfDNA Max 50 Reagent Kit
PN 404000
Summary Product Benefits:
Reagents only for input sample volumes (like plasma and urine) from 21 mL - 50 mL.
- Flexibility - The same cfDNA Max 50 Revolution reagents without the nRicher Cartridges
- Efficiency - Get full utilization of all your cfDNA Max 50 kit's large-capacity nRicher Cartridges
The IVD-labeled Revolution cfDNA Max 50 Reagent Kit provides supplemental reagents to enable the use of any excess Revolution nRicher Cartridges in the cfDNA Max 50 Kit shown above. Revolution nRicher Cartridges are not included in the reagent kit. This kit has sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 21-30 mL preps, or
- (18) 31-40 mL preps, or
- (12) 41-50 mL preps
Revolution cfTNA Max 20 Kit
PN 408500
Summary Product Benefits:
For input sample volumes (like plasma and urine) from 1 mL - 20 mL. Includes nRicher Cartridges and kit reagents.
- Better Performance - higher yields of cfTNA means greater assay sensitivity and fewer 'QNS' assay failures
- Greater Flexibility - widest range of input sample volume (1 mL - 20 mL) of any automated extraction kit with the unique nRicher Cartridge
- Easier Workflow - as compared to other methods which require tedious vacuum manifolds, tube extenders, manual pre-concentration steps, re-elutions, and extraction sample pooling for larger per-sample volumes
The IVD-labeled Revolution cfTNA Max 20 Kit may be used to isolate circulating cell-free Total Nucleic Acid (cfTNA) or cfRNA, using an optional DNAse digestion step. The kit includes (24) Revolution nRicher Cartridges and sufficient reagents to perform the following cfTNA extractions from plasma or urine:
- (24) 1-5 mL preps, or
- (12) 6-10 mL preps, or
- (8) 11-15 mL preps, or
- (6) 16-20 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Revolution cfTNA Max 20 Reagent Kit
PN 401500
Summary Product Benefits:
Kit reagents only for input sample volumes (like plasma and urine) from 1 mL - 20 mL.
- Flexibility - The same cfTNA Max 20 Revolution reagents without the nRicher Cartridges
- Efficiency - Get full utilization of all your kit's nRicher Cartridges
The IVD-labeled Revolution cfTNA Max 20 Reagent Kit provides supplemental reagents to enable the use of any excess Revolution nRicher Cartridges in the cfTNA Max 20 Kit shown above. Revolution nRicher Cartridges are not included in the reagent kit. This kit has sufficient reagents to perform the following cfTNA extractions from plasma or urine:
- (24) 1-5 mL preps, or
- (12) 6-10 mL preps, or
- (8) 11-15 mL preps, or
- (6) 16-20 mL preps
Revolution cfTNA Max 50 Kit
PN 406500
Summary Product Benefits:
Similar to the Revolution cfTNA Max 50 Kit, but designed for larger sample volumes of 21 mL - 50 mL. Includes nRicher Cartridges and kit reagents.
- Extract from larger volumes - designed for sample volumes >20 mL in a single extraction
- Same performance, flexibility, and workflow advantages
- Runs on the Revolution Plus Processor
The IVD-labeled Revolution cfTNA Max 50 Kit includes (24) 100 mL nRicher Cartridges and sufficient reagents to perform the following cfTNA extractions from plasma or urine:
- (24) 21-30 mL preps, or
- (18) 31-40 mL preps, or
- (12) 41-50 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Revolution cfTNA Max 50 Reagent Kit
PN 405500
Summary Product Benefits:
Reagents only for input sample volumes (like plasma and urine) from 21 mL - 50 mL.
- Flexibility - The same cfTNA Max 50 Revolution reagents without the nRicher Cartridges
- Efficiency - Get full utilization of all your cfTNA Max 50 kit's large-capacity nRicher Cartridges
The IVD-labeled Revolution cfTNA Max 50 Reagent Kit provides supplemental reagents to enable the use of any excess Revolution nRicher Cartridges in the cfTNA Max 50 Kit shown above. Revolution nRicher Cartridges are not included in the reagent kit. This kit has sufficient reagents to perform the following cfTNA extractions from plasma or urine:
- (24) 21-30 mL preps, or
- (18) 31-40 mL preps, or
- (12) 41-50 mL preps