New nRicher Cartridge features and benefits image with Transparent Background_4Apr24

The integrated nRicher Cartridge -

maximizes yield of cfDNA, cfRNA, and CTCs primarily in two ways:


  1. Integration of the Sample Tube with a detachable Capture Tube and Mag Capsule, enables extraction and enrichment of rare analytes without the yield-lowering sample transfers between multiple plasticware containers found in other methods. This increases yield at any sample volume.

  2. An unequaled sample range from as little as 1 mL to 100 mL of samples depending on  the application. The ability of the nRicher Cartridge to process larger volumes in a single extraction without resorting to yield-lowering schemes like eluate pooling from multiple separate extractions found in other methods increases yield for higher sample volumes


The Revolution Plus

Exclusively uses nRichDX nRicher Cartridges in Revolution Kits to process from 1-12 samples in a single run using a semi-manual workflow.

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Features and Benefits of The Revolution Sample Prep System

Accuracy exceeding the competition

Recover more detectable mutations from liquid biopsies. The Revolution System was specifically designed to address the challenges of liquid biopsy. Competitor kits can't handle the same sample volumes and lack the recovery efficiencies built into The Revolution System for sample preparation.

Higher yields... even at low volumes

Using 5 mL of plasma, nRichDX had a significantly higher cfDNA yield than Competitor A and exponentially more yield at 15 mL


Highly efficient cfDNA extraction

Get more cfDNA from your extractions with the patented Revolution System. The adjacent figure shows an 88% recovery rate (175 ng/extraction) for the Revolution System after accounting for the 35 ng/mL background (measured in samples 5-8).

Revolution System cfDNA yield is proportionate across all sample input volumes

Recovery rates increase linearly relative to input size. Samples 1-4 all demonstrate linear recovery rates across the 5 mL-20 mL volume range, despite individual variability in cfDNA abundance (obtained using the Revolution System and the Revolution cfDNA Max 20 Kit).

Revolution System proportionately extracts the actionable cfDNA across all sample volumes


Broad compatibility across applications

Blood, plasma, urine, sputum, lavage and other biological fluids are all enrichable with The Revolution System. This broad range supports both current and forthcoming test.

Sample Types and Applications_Platform Page version

Revolutionary results for demanding diagnostic applications


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